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THC, along with CBD, are the predominantly active components of the cannabis plant. THC is the main psychoactive component and binds to the CB1 receptors in the brain. These receptors are part of our body's natural endocannabinoid system. Unlike opioid pain medications, there are no receptors for THC in the part of the brain that controls respiration or heart rate. Because of this, there have been no deaths reported with the use of cannabis. A person cannot overdose on cannabis, although you may get increased psychoactivity.
There are different strains of the cannabis plant. There are two schools of thought regarding these strains. One is that the difference between the Sativa and Indica plant is due to the environment where it grows. One in a dry, hotter climate and the other in a more tropical climate. It is also felt that the effect of the two are similar, just the growth pattern is different. The other school of thought is as follows:
The Sativa strain is known to effect a person's feelings and thoughts and stimulates creativity. It can also elevate your mood and reduce depression. It may also increase your appetite. For some people, it may increase anxiety and paranoia, due to it's uplifting effects. For this reason, most people use this strain during the daytime only.
The Indica strain primarily works its effects on the body by producing calming and sedated feelings. For this reason it is best used in the evening for relaxation, sleep and stress reduction. It can also reduce anxiety symptoms.
There are Hybrid strains, which combine both the Sativa and Indica strains. Whichever strain is more dominant in the Hybrid, determines which strain will dominate in the effects.
THC is also available in combination with CBD. The CBD counteracts the psychoactivity of the THC. Also, the combination of the two together will give a more powerful effect on the body than each given separately. For this reason, the physician may recommend a certain ratio of THC:CBD, for your particular issue(s).
Your recommending physician will determine what strain is best for your condition. You may be offered many different products and strains at the dispensary, but it is highly recommended that you adhere to what the physician wants you to use. This assures that you obtain the best positive medical effects possible.